Bergenia ligulata is a perennial herb with short, thick, fleshy and procumbent stems and very stout root stock. Leaves are ovate or round and cm long. Bergenia ligulata wall whole plant is used for kidney and bladder stones, urinary problems. (8,9,) It has been reported to exhibit various pharmacological. Pashanabheda- Bergenia ligulata (Wall.) Engl. is a small plant used in the treatment of renal calculi, retention of urine, wounds, diseases of the.

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In summary, the best bioactive fraction DCM fraction of mother extract of B. Journal of Scientific and Industrial Research ; The treatment of mother extract and DCM fraction alone reduced calcium in the urine, serum, and kidney homogenate in urolithiasis rats and thereby prevents the formation and aggregation of stone.

The hepatoprotective effects against galactosamine-intoxicated rat hepatocytes might be by inhibiting the release of glutamic pyruvic transaminase and sorbitol dehydrogenase as well as by increasing RNA synthesis Vessels with simple pits have perforation plates on one end or at both ends and tracheids have helical thickenings 11, 13, 14, Aqueous extract of B.

All the rats were randomly housed under hygienic conditions in polypropylene cages and allowed to acclimatize for one week. Since the ancient time of human history plants have been used to treat various ailments, for the reason that the herbals have been generally considered to be safe and nontoxic as compared to synthetic medicine. Antioxaluria activity Pendse et al.


Hot water extract of whole dried plant of B.

Plants are considered as state-of-art laboratories capable of biosynthesizing number of biomolecules of different chemical classes. It also contains sterols viz.

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Mother extracts showed Hepatoprotective activity The assessment of hepatoprotective activity was carried out on male albino rats of wistar strain The antiurolithiasis activity of mother extract and the best bioactive fraction of B.

The ethylene glycol is metabolized to acidic metabolites such as oxalic acid, hippuric acid, benzoic acid, and formic acid which cause metabolic acidosis. Our reports are in agreement with the studies previously reported on the antiurolithiasis potency of B. Medicine from the plant is the alternative and last source for new drug and it remains the last choice to the physician for better relief.

Ethylene glycol induced renal calcium oxalate crystal deposition is the most apposite animal model that is regularly used to mimic the stone formation in humans. Bergenia Moench- elephant ear Species: International Journal of Crude Drug Research ; Crystals as small as 3.

Bergenia ligulata – Wikipedia

Decoction of fresh roots of B. Activities of bergenin When bergenin was incubated into hepatocyte medium for 14 hrs with 1. The administration of Ligulat.

The abdomen of the animal ebrgenia cut to remove both kidneys of selected animal from each group. This study shows that scanning of calcium oxalate crystals under the confocal microscope is a powerful technique for determining the mode of action of any drug which inhibits nucleation and aggregation for calcium oxalate crystals precipitation. The microscopic evaluation of collected urine was done at 10x magnification. The ex vivo study represents one of the first uses of plasma rather than using synthetic urine to check the antiurolithiasis potential of any herbal formulation.


Administration of ethylene glycol 0. Cardiotoxic, antidiuretic and CNS depressant action of B. Studies on Nepalese crude drugs on the phenolic constituents of the rhizomes of Bergenia ciliata Haw. Antiviral activity of some plants used in Nepalese Traditional Medicine. Abstract Dried bergenka of Bergenia ligulata pashanbhed is commonly used as a traditional herbal medicine with a wide range of therapeutic applications including urolithiasis.

After urine collection, total urinary excretion of calcium, phosphate, oxalate, uric acid, and albumin was measured by various biochemical kits Span Diagnostics Ltd. Catechin was found in both mother extract and DCM fraction, for which it can protect against oxidative injury by oxalate and crystal deposition along with its protective effect against calculi formation [ 17 ]. Antibacterial activity of some Indian Medicinal Plants.