Brain cancer module: QLQ-BN Scope. The brain cancer module is meant for use among brain cancer patients varying in disease stage and treatment. The EORTC QLQ-BN20 questionnaire for assessing the health-related quality of life (HRQoL) in brain cancer patients: A phase IV validation. To be used in conjunction with the EORTC QLQ-C30 for measuring the health- related quality of life in patients with brain cancer.
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We acknowledge as a limitation that the observed correlations between the anchors and HRQoL scores were not strong. Descriptive statistics summarizing the distributions of HRQoL scores at baseline are given in Table 2.
Prosthetics and Orthotics International. Prognostic implications of residual disease tumor-infiltrating lymphocytes and residual cancer burden in triple negative breast cancer patients after neo-adjuvant chemotherapy. Quality of life of lung cancer patients: The estimates generally agree with the estimates of 5—10 units of the QLQ-C30 scales we considered and as proposed by Osoba et al.
The MMSE [ 21 ] is a test with a point maximum score, which is used to screen for cognitive impairment. Based on PS, our findings support the following integer estimates of the MCID for improvement and deterioration, respectively: Effects of radiotherapy on cognitive function in patients with low-grade glioma measured by the Folstein Mini-Mental State Examination.
JewittWarren P. CoateChristine MasseyNatalie C. Citing articles via Web of Science Thresholds of 1 SEM have also been suggested [ 11 ].
Differences that are statistically significant are indicated by asterisk. For all these scales, a higher score represents worse HRQoL. For comparison purposes, four distribution-based approaches were applied: Dieta BrandsmaMartin J.
Qlq-bh20 article has been cited by 1 Prospective assessment of quality of life in adult patients with primary brain tumors in routine neurooncology practice Budrukkar, A. Functional assessment eirtc cancer therapy-brain questionnaire: For illustration, the first difference in PF mean change of adjacent categories is obtained as 4.
These 2 questionnaires were then compared with the original EORTC questionnaire and the second intermediate questionnaire was formed. Qual Life Res ; Benchmarks for interpreting differences between groups cross-sectionally may differ from those for interpreting changes over time within groups [ 2 ]. Possible limits to the universality of the one-half standard deviation comment.
The development and psychometric validation of a brain cancer quality-of-life questionnaire for use in combination with general cancer-specific questionnaires. Van Den Bent, R. In large sample sizes, statistically significant results can be obtained when numerical differences in HRQoL change scores are small and not likely to be clinically meaningful.
Changes in MMSE were grouped as: Analysis pertaining to physical and role functioning scales was restricted to Trial 1, which used version 3, the current version [ 19 ]. For each analysis, patients with data on an anchor and HRQoL scores at 2 or more time points were included. From This Paper Figures, tables, and topics from this paper.
Anchor-based methods link HRQoL measures to external criteria, either to a known indicator that has clinical relevance [e.
EORTC Quality of Life Questionnaire – Brain Cancer Module (EORTC QLQ-BN20)
The second intermediate questionnaire was subsequently administered in 10 patients with brain tumors who had never seen the questionnaire before, for pilot-testing. This questionnaire was then given to two more translators who translated this questionnaire back into English. In general, the mean changes in HRQoL within each anchor-defined category were in the expected direction. Quality of life of breast cancer patients in Taiwan: It furthers the University’s objective of excellence in research, scholarship, and education by publishing worldwide.
In both trials, HRQoL was measured as a secondary end point at baseline, during treatment, and on several follow-up occasions after the end of treatment. P values, does not provide information about the clinical meaningfulness.
EORTC QLQ-BN20 – EORTC Quality of Life Questionnaire – Brain Cancer Module
Neoplasms Search for additional papers on this topic. For permissions, eorfc email: Attention deficit hyperactivity disorder Primary malignant neoplasm of brain Bipolar Disorder pediatric intracranial germ cell brain tumor. Determining clinically important differences in health status measures: Related articles in Web of Science Google Qlq-bn2.
The QLQ-BN20 contains 20 items, 13 of which aggregate into four scales assessing future uncertainty, visual disorder, motor dysfunction MDand communication deficit. Measurement of health status: Qlq-nb20 to cite this article: Receive exclusive offers and updates from Oxford Academic. In this study, changes in MMSE of 6 or more points were viewed as rather too large for the purpose of determining the MCID and were therefore excluded from the analysis, as were the changes in PS of two or more categories in order not to overestimate the MCID.
Quality of life and physical limitations in primary brain tumor patients Mariana Rodrigues GazzottiSuzana M. Online since 1 st AprilNew website qlq-bm20 since 6 th Aug Thus, every study contributing to this question is important. This article has been cited by. Eoryc, the changes that we are calling MCIDs are based on the definitions and clinical anchors that we have applied, e. Selected baseline demographic and clinical characteristics of the patients.
Identification of MCIDs was carried out using two clinical anchors: Related articles in PubMed Late systemic symptoms in head and neck cancer survivors.